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Insulin treatment for type 2 diabetes

For some people living with type 2 diabetes, either the pancreas doesn't produce enough insulin, or the body can't use insulin effectively (known as insulin resistance)1,2. In this case, your healthcare professional may recommend that you start insulin treatment to help manage your blood sugar levels1,2. Around 15% of people with type 2 diabetes require insulin therapy – that’s  63 million people globally3!

There are various different insulin treatment options, and your routine will be tailored to your specific needs. Keep reading to learn about the different types of insulin, how they differ and what they are used for, as well as how a lot of people feel about starting insulin therapy for type 2 diabetes. 

How long does insulin work for?4,5

To start with, it is important to know that there are different types of insulin, which differ in three key ways:

How quickly they work

(onset of action)

When they have the greatest effect

(time of peak action)

How long they work

(duration of action)

This means the duration of your insulin's effectiveness may vary depending on your specific treatment plan. Depending on your needs, your healthcare professional may recommend that you begin on a specific type of insulin. Your treatment may need to be adjusted over time to help manage your blood sugar levels more effectively.

But don’t worry! Whichever insulin your healthcare professional recommends, they will also help you establish a personal routine to keep your blood sugar levels in a healthy range throughout the day.

We look at two of the most common forms of insulin you may use in the management of your type 2 diabetes below ↓

What are long-acting insulins? What are they used for?

Most people with type 2 diabetes who move on to insulin treatment start with a long-acting insulin. These are often called basal or 'background' insulins because they have a slow onset and keep a low, consistent level of insulin in your blood over an extended time6.

Long-acting insulins work to keep your blood sugar levels steady throughout the entire day6 – including between meals and when you sleep. Because of their long duration of action, they are usually taken only once or twice daily.

What are short acting insulins? What are these used for?

If you’re living with type 2 diabetes, your blood sugar levels might rise rapidly when you’re eating a meal. Sometimes, long-acting insulin isn't enough to control these 'spikes' and you may need to add mealtime insulin to keep your blood sugar levels under control6.

Mealtime or bolus insulins are rapid or fast-acting insulins that you inject just before you eat to manage blood sugar spikes6. They are taken in addition to a long-acting or basal insulins and together, they are sometimes called 'basal-bolus insulin'. You may start with just one mealtime insulin injection per day, usually with your main meal5,7. Your healthcare professional will advise you to add more mealtime injections if necessary.

Is it normal to feel anxious about starting insulin therapy?

Regardless of the type of insulin you are prescribed, moving on to insulin treatment can seem overwhelming and these feelings are completely normal8. If you’re worried about starting injections, or fitting them into your day-to-day routine, just remember – you are not alone. For some people, these worries are enough to stop them from getting the treatment they need, but this can ultimately be damaging to their health. Insulin as a treatment for type 2 diabetes can help reduce complications linked to uncontrolled blood sugar levels over time, including cardiovascular disease, kidney disease, permanent vision problems and nerve damage2.

Talk to a healthcare professional to help you feel comfortable and confident as you begin your insulin journey, to ensure you receive the care you need.

Still have questions around starting insulin therapy for your type 2 diabetes? Read through our guide and take notes on questions you can ask your healthcare professional here.

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References
  1. Petersen MC, Shulman GI. Mechanisms of Insulin Action and Insulin Resistance. Physiol Rev. 2018;98:2133-2223.
  2. International Diabetes Federation. IDF Diabetes Atlas Report 10th Edition 2021. Available at: http://www.diabetesatlas.org/ Last accessed: September 2024.
  3. World Health Organisation. Keeping the 100-year-old promise: making insulin access universal. Available at: https://www.who.int/publications/i/item/9789240039100 Last accessed: September 2024.
  4. CDC (U.S. Centers for Disease Control and Prevention). Types of Insulin. Available at: https://www.cdc.gov/diabetes/basics/type-1-types-of-insulin.html Last accessed: September 2024.
  5. Holt RIG, DeVries JH, , et al. The Management of Type 1 Diabetes in Adults. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2021;44:2589-2625.
  6. Donnor T, Sarkar S. Insulin- Pharmacology, Therapeutic Regimens and Principles of Intensive Insulin Therapy. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, et al., eds. Endotext. South Dartmouth (MA); 2000.
  7. Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes-2024. Diabetes Care. 2024;47:S158-s178.
  8. Peyrot M, Barnett AH, Meneghini LF, et al. Insulin adherence behaviours and barriers in the multinational Global Attitudes of Patients and Physicians in Insulin Therapy study. Diabet Med. 2012;29:682-689.

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