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Type 1 vs type 2 diabetes: What’s the difference?

If you’ve been diagnosed with diabetes, you might have a lot of questions about what exactly this means – that’s normal! To start with, you need to understand what type of diabetes you have. The most common are type 1 and type 2. While they might sound similar, there are some key different in how they affect your body:

Differences between type 1 and type 2 diabetes at a glance

  Type 1 diabetes Type 2 diabetes
What’s happening in your body Your immune system attacks the cells in your pancreas that make insulin. As a result, your body can’t make insulin, or enough of it, and therefore can’t process blood sugar1. Your insulin production is reduced over time due to high blood sugar levels. The insulin your body makes becomes less effective and the pancreas cannot keep up with demand1.
Risk factors

We don’t know the exact cause of type 1 diabetes. It has been linked to2,3:Type 2 diabetes has been linked to a several factors, including: 

  • Genetics
  • Gut microbiome
  • Environmental factors

Type 2 diabetes has been linked to a several factors, including: 
  • Genetics
  • Stress
  • Certain medications
  • Diet and lifestyle
  • Age (most common in those over 40)
Onset of symptoms Symptoms usually appear quickly1.

Symptoms for type 2 diabetes can be less noticeable and appear more slowly2.

Treatments People with type 2 diabetes take daily insulin injections1. People with type 2 diabetes typically start with lifestyle changes; if these are not enough to manage blood sugar levels, medication may also be prescribed1

Read on to dive deeper into the differences in symptoms, treatments and how you can manage your disease!

What are the different types of diabetes?

It is estimated that 537 million people have diabetes worldwide. There are two main types – type 1 and type 2. Type 2 diabetes is by far the most common, accounting for over 90% of cases1. As they have very different causes, the symptoms and treatment will vary in type 1 vs type 2 diabetes. That’s why it’s important to understand your own disease and consult your healthcare professional, to help you manage it effectively. 

Type 1 vs type 2 diabetes: What are the causes?

Type 1 diabetes is when your immune system attacks and destroys cells in your pancreas that make insulin. As a result, your body can’t make insulin, or makes very little, and without insulin, your body can’t process blood sugar. Instead of being absorbed into your cells and used as energy, this blood sugar builds up in your bloodstream. This can cause damage to areas in the body such as the eyes, blood vessels, kidneys, and heart, leading to diabetes symptoms and complications1,4.

Type 2 diabetes is when your insulin production is reduced over time due to high blood sugar levels. In response to high blood sugar levels, the insulin your body makes becomes less effective, and your pancreas has to work overtime to produce more. This is called insulin resistance1. Over months, and even years, the pancreas becomes tired and cannot keep up with the demand1.

Type 1 vs type 2 diabetes: What are the risk factors?

Type 1 diabetes risk factors

Experts still do not know exactly what causes type 1 diabetes; however, the following are thought to be linked:

genetics

Genetics

There is not one single gene that can be inherited. It is thought a number of genes increase the chance of developing type 1 diabetes3.

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Environmental factors

The rates of type 1 diabetes are increasing, suggesting environmental factors contribute to disease development; however, lifestyle and weight are not thought to be linked3.

microbiome

Gut microbiome

The gut microbiome and childhood diet may all play a part; however, research is ongoing3.

age

Age

While people of all ages can experience onset of type 1 diabetes, it is more commonly first diagnosed in children and those under the age of 402.

Type 2 diabetes risk factors

There are several factors that can increase your risk of developing type 2 diabetes, including5,6:

age

Age

If you are over the age of 406.

genetics

Genetics

Our building blocks, also known as our genes, may increase the likelihood of developing type 2 diabetes, e.g., genes involved in blood glucose control and insulin secretion7. You are more likely to have these genes if one of your family members is living with diabetes6.

stress

Stress

When we are stressed, hormones are released that can lead to the raising of blood sugar levels. If you are stressed for a long period of time, your blood sugar levels may remain outside the normal range8.

medication

Medication

Some medications such as corticosteroids and statins, used for the treatment of multiple conditions, can have side effects such as altering insulin secretion and increasing glucose production9.

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Diet and lifestyle choices

Several lifestyle factors, like an unhealthy diet and a sendentary lifestyle which are also linked to overweight and obesity, have been associated with an increased risk of developing type 2 diabetes10,11

Type 1 vs type 2 diabetes: What are the symptoms?

Type 1 diabetes symptoms

Symptoms can vary from person to person12
Symptoms of type 1 diabetes

If you or a loved one notices any of these symptoms please consult a healthcare provider.

Type 2 diabetes symptoms

Symptoms in type 2 diabetes can be the same as above1, but could also include:

  • Itching around your penis or vagina, or repeatedly getting thrush13
  • Cuts or wounds taking longer to heal13

Diabetes symptoms can be similar for both type 1 and type 2, but in general, symptoms for type 2 diabetes can be a lot less noticeable, or you may not experience any, which can result in a delayed or missed diagnosis1. While symptoms for type 1 diabetes tend to appear quickly, those for type 2 diabetes can appear more slowly, which can also lead to them being missed2.

Find out more about diabetes symptoms here. If you or a loved one notices any of the symptoms mentioned please consult a healthcare professional.

Type 1 vs type 2 diabetes: What are the treatments?

  • People living with type 1 diabetes require daily insulin injections to manage their disease1
  • Treatment options for type 2 diabetes focus on lifestyle changes; if these are not enough to manage blood sugar levels, medication may also be prescribed1

Type 1 diabetes

As people living with type 1 diabetes make little to no insulin, daily insulin injections are required to help manage blood sugar levels. You can live a healthy life, and delay or prevent diabetes-related complications if you monitor your blood sugar levels, visit a healthcare professional regularly, and get support from family and/or loved ones1,4. To find out more about treatment for type 1 diabetes, read our article here.

Type 2 diabetes

A key part of treating type 2 diabetes is trying to lead a healthy lifestyle, which may include following a healthy and balanced diet, taking part in regular physical activity, avoiding smoking and trying to maintain a healthy body weight1.

Type 2 diabetes is a progressive disease1. Over time, many find that lifestyle changes alone no longer enable them to manage their type 2 diabetes. Healthcare professionals may recommend medications based on each patients' individual needs1.

Your doctor may also recommend using insulin if prior therapies are unable to prevent prolonged high blood sugar levels1

Type 1 vs type 2 diabetes: Insulin therapy

There are 2 main types of insulin: basal (background) insulin, which keeps a low, consistent level of insulin in your blood throughout the day14, and bolus (mealtime) insulin, which is used to help control your blood sugar spikes after eating14.

  • People with type 1 diabetes will have an insulin treatment regime with both basal and bolus insulin14.
  • People with type 2 diabetes will be prescribed basal insulin to start with by their healthcare professional. Sometimes, this type of insulin isn't enough to control 'spikes' in your blood sugar levels at mealtimes, in which case you may also be prescribed bolus insulin to keep your blood sugar levels under control14

Fears of starting insulin therapy

It’s completely normal to feel nervous about starting insulin therapy. Unfortunately, around half of people with type 2 diabetes delay insulin therapy initiation by over two years. This can be for many reasons, but for some, concerns about injections, the potential side effects and how this will fit into daily routines can be a driving factor15.

However, ensuring insulin is initiated on your healthcare professionals recommendation is important to reduce the chances of complications such as cardiovascular disease, kidney disease, permanent vision problems, and nerve damage16.

Learning more about how insulin therapy works can be a huge help in overcoming your anxieties and getting you feeling confident about starting your insulin journey. 

Remember, it is important to speak to your healthcare professional if you are concerned about your current diabetes treatments. 

Still have questions around starting insulin therapy for your type 2 diabetes? Read through our guide and take notes on questions you can ask your healthcare professional here.

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References
  1. International Diabetes Federation. IDF Diabetes Atlas Report 10th Edition 2021. Available at: https://diabetesatlas.org/atlas/tenth-edition/ Last accessed: October 2024. Available 
  2. Diabetes UK. Differences between type 1 and type 2 diabetes. Available at: https://www.diabetes.org.uk/diabetes-the-basics/differences-between-type-1-and-type-2-diabetes Last accessed: October 2024.
  3. Diabetes UK. Research spotlight - what causes type 1 diabetes? Available at: https://www.diabetes.org.uk/research/research-round-up/research-spotlight/research-spotlight-what-causes-type-1-diabetes Last accessed: October 2024.
  4. CDC (U.S. Centers for Disease Control and Prevention). What is Type 1 Diabetes. Available at: https://www.cdc.gov/diabetes/basics/what-is-type-1-diabetes.html Last accessed: October 2024.
  5. CDC (U.S. Centers for Disease Control and Prevention).Diabetes Risk Factors. Available at: https://www.cdc.gov/diabetes/risk-factors/index.html. Last accessed: October 2024.
  6. Diabetes UK. Diabetes risk factors. Available at: https://www.diabetes.org.uk/preventing-type-2-diabetes/diabetes-risk-factors Last accessed: October 2024.
  7. Lyssenko V, Groop L, et al. Genetics of Type 2 Diabetes: It Matters From Which Parent We Inherit the Risk. Rev Diabet Stud. 2015;12(3-4):233-242.
  8. Sharma K, Akre S, Chakole S, et al. Stress-Induced Diabetes: A Review. Cureus. 2022;14:e29142.
  9. Heurtebize M-A, Faillie J-L. Drug-induced hyperglycemia and diabetes. Therapies. 2024;79:221-238.
  10. Grant B, Sandelson M, Agyemang-Prempeh B, et al. Managing obesity in people with type 2 diabetes. Clin Med (Lond). 2021;21:e327-e231.
  11. Whitmore C. Type 2 diabetes and obesity in adults. Br J Nurs. 2010;19:880, 882-886.
  12. NHS. Diabetic ketoacidosis. Available at: https://www.nhs.uk/conditions/diabetic-ketoacidosis/ Last accessed: October 2024.
  13. NHS UK. Type 2 diabetes. Symptoms. Available at: https://www.nhs.uk/conditions/type-2-diabetes/symptoms/ Last accessed: October 2024.
  14. Donnor T, Sarkar S. Insulin- Pharmacology, Therapeutic Regimens and Principles of Intensive Insulin Therapy. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Holland J, et al., eds. Endotext. South Dartmouth (MA); 2000.
  15. Peyrot M, Barnett AH, Meneghini LF, et al. Insulin adherence behaviours and barriers in the multinational Global Attitudes of Patients and Physicians in Insulin Therapy study. Diabet Med. 2012;29:682-689.
  16. Ceriello A. The possible role of postprandial hyperglycaemia in the pathogenesis of diabetic complications. Diabetologia. 2003;46 Suppl 1:M9-16.

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